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Introduction Cancer therapy has evolved throughout the decad
2019-06-01
Introduction Cancer therapy has evolved throughout the decades and is beginning to branch off into new and exciting fields including immunotherapy. The hope of this new field stems from the lack of success of chemotherapy in general. Chemotherapy\'s cytotoxic characteristics were regarded as one of
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Conversion of cholesterol to bile
2019-06-01
Conversion of cholesterol to bile acids is the only significant catabolic pathway for elimination of excessive cholesterol in our body. Bile acids have long been recognized as important physiological agents that facilitate luteolin of dietary fats, steroids, drugs, and lipid soluble vitamins during
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Importa acentuar que la colonialidad no descansa sobre la
2019-05-31
Importa acentuar que la colonialidad no descansa sobre la economía como tal, y menos sobre la literatura, sino sobre el devenir de la episteme racial gestada durante el legado colonial latinoamericano. Con ello busca no sólo, o no tanto, una relectura de la historia latinoamericana sino más bien una
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Se trata de concepciones diferentes
2019-05-31
Se trata de concepciones diferentes de la democracia. Przeworski asume la democracia desde un concepto procesual centrado en las elecciones, y la define como “un régimen en el cual los cargos de gobierno se cubren como consecuencia de contiendas electorales. Un régimen sólo es democrático si se le p
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br Discussion To our knowledge we
2019-05-31
Discussion To our knowledge, we report for the first time t(8;21) acute myeloid leukemia presenting as severe aplastic anemia. t(8;21)(q22;q22) is present in 5–10% of all AMLs, and includes variety of subtypes with varying pathology, and clinical presentations, ranging from circulating blast in p
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Missed cases have been reported who had
2019-05-31
Missed cases have been reported who had an initially elevated C5DC concentration that normalized on a repeated sample. Such a result may be caused by secondary carnitine depletion. To avoid carnitine depletion, we propose that the carnitine loading test be used to assist diagnosis of GA-1. Although,
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Introduction Atrial fibrillation AF is
2019-05-31
Introduction Atrial fibrillation (AF) is a common cardiac arrhythmia that becomes more prevalent with age [1] and is associated with an increased long-term risk of stroke, order JQ1 failure, and all-cause mortality [2]. Since Einthoven recorded the electrograms in 1906 [3], AF has widely been reco
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Although preoperative rehabilitation may have a strong impac
2019-05-31
Although preoperative rehabilitation may have a strong impact on survival if additional patients are qualified for curative resection, yet strong evidence remains lacking to support the regimens for patients who have lung cancer. This may be due to, in part, the relatively brief meclofenamate of ti
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Two studies are ongoing that promise to be paramount in
2019-05-31
Two studies are ongoing that promise to be paramount in the prescription of dexamethasone in the prophylaxis of pain flare. NCIC CTG is currently investigating the use of 8mg dexamethasone daily on the day of treatment and four days post-treatment versus placebo of the same duration (NCT01248585) [1
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ampar Paralelamente Chucho Hegel increpa al Profesor
2019-05-30
Paralelamente, Chucho Hegel increpa al Profesor: “Sin dejar de ser el mismo, te has convertido en el otro como el blanco que se pinta de negro en el teatro bufo”. Pone, así, sobre el tapete, el que quizá sea el mayor de los demonios contra los que lucha el Profesor, personaje, éste, que deja espacio
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Na defini o da Secretaria Nacional de
2019-05-30
Na definição da Secretaria Nacional de Políticas de Promoção da Igualdade Racial, vinculada atualmente ao Ministério dos Direitos Humanos do governo federal, as ações afirmativas são políticas públicas que têm como objetivo purchase GSK-J1 sodium salt correção de desigualdades raciais acumuladas ao
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Now consider a Special Report by the WHO Ebola Response
2019-05-30
Now consider a Special Report by the WHO Ebola Response Team. In it, the authors rightly—if not tautologically—suggest that shortening the delay to isolation of Ebola virus disease suspects would lead to quicker overall outbreak containment, yet they fail to adequately discuss the reality that suspe
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In DC from A group only few
2019-05-30
In DC from A group only few genes appeared to be significantly and highly modulated (10 out of 84). The HIV natural ligands CCL4 and CD4, the HIV induced transcription factor IRF1 as well as the apoptotic genes BAD and CASP8 resulted down-regulated compared to monocytes at all the considered time po
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br Conflict of interest br Introduction Patients with struct
2019-05-30
Conflict of interest Introduction Patients with structural heart disease have an increased risk of sudden cardiac death, secondary to ventricular tachyarrhythmias in most cases. Implantable cardioverter–defibrillators (ICDs) are the treatment of choice. However, ventricular tachyarrhythmias ca
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br Results Compared to the
2019-05-30
Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB
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