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Human p MAPK is stimulated by various
2019-04-22
Human p38 MAPK is stimulated by various inflammatory cytokines and cellular stresses [46]. Especially, the p38 MAPK signaling pathway is a crucial modulator of proinflammatory cytokine biosynthesis at the transcriptional and translational levels [46]. Furthermore, studies revealed that p38 MAPK regu
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br Case A year old man was referred for the
2019-04-22
Case A 45-year-old man was referred for the management of sudden-onset tachycardia. He had experienced 3 episodes of palpitation attacks, lasting for a couple of hours each, during the last 6 months. A regular, wide QRS complex tachycardia (WCT) at 150beats/min with a prominent retrograde P wave
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br Methods br Results br
2019-04-22
Methods Results Discussion Conclusions Conflict of interest Acknowledgments We thank Mr. John Martin for his linguistic assistance, and Mr. Jiro Suto for technical assistance in developing the QRS-T subtraction program. This study was supported by the Fukuda Foundation for Medical
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The first variant in the non spine topic describes a
2019-04-22
The first variant in the non-spine topic describes a patient with an excellent performance status, a favorable life expectancy, and an asymptomatic mCAP lesion which does not pose an obvious risk for pathologic fracture. While the authors acknowledge that research has begun to determine whether pati
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Several anti platelet therapies have been evaluated in the c
2019-04-22
Several anti-platelet therapies have been evaluated in the context of bone metastasis. In vitro, a dual anti-platelet treatment using the soluble ADPase APT102 and an inhibitor of TxA2 synthesis (Aspirin) markedly affected tumor cell-induced platelet aggregation without altering tumor cell viability
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Estas ideas permanecieron vigentes durante mucho tiempo
2019-04-22
Estas ideas permanecieron vigentes durante mucho tiempo antes de la revolución científica desatada por el racionalismo. Un ejemplo es cómo las nociones neumáticas —derivadas de la idea de que el mundo fue creado por un soplo divino— todavía son palpables en el Primero sueño de sor Juana cuando inici
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Acerca do cinema cubano Sol Aymara em
2019-04-22
Acerca do cinema cubano, Sol Aymara, em artigo denominado Breve mirada al cine cubano, sustentou que houve um desenvolvimento significativo da cinematografia do país em razão do apoio decisivo da Revolução e do próprio Fidel Castro, que mostrou interesse particular em desenvolvê-lo, contribuindo par
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br Discussion The natural history of PMF is characterized
2019-04-22
Discussion The natural history of PMF is characterized by the possibility of blastic transformation in approximately 20% of all the cases [9]. Several factors might predict leukemic transformation, including percentage of circulating blasts, low platelets count and the presence of an unfavorable
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br Introduction Since Reekers and Bolia introduced subintima
2019-04-22
Introduction Since Reekers and Bolia introduced subintimal angioplasty, the trans-subintimal route has become the preferred technique to advance the guidewire through a totally occluded and often heavily calcified lesion, especially in the aortoiliac segment. The technical failure was seen in 20–
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No que concerne ao territ rio partimos do princ pio
2019-04-20
No que concerne ao território, partimos do princípio de que os traços culturais de um grupo humano são inseparáveis de suas estruturas espaciais, sendo lgk974 manufacturer apreensão do espaço crucial para que os grupos étnicos construam e comuniquem suas identidades e diferenças. Para ElHajji, o des
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br Risk stratification in BrS
2019-04-20
Risk stratification in BrS Many risk markers have been reported in patients with high-risk BrS. Clinical markers include family history of sudden death at a young age (refractory hdac inhibitor in the right ventricle ( Treatment Asymptomatic patients Risk stratification and the optimal thera
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mass molarity calculator In the American College of Chest
2019-04-20
In 2013, the American College of Chest Physicians provided a guideline to the preoperative physiological assessment of patients being considered for surgical resection of lung cancer. It has been recommended that patients must be assessed by a multidisciplinary team before operation, regardless of a
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The effects of zoledronic acid are most likely due to
2019-04-20
The effects of zoledronic ionomycin are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal surface. Wher
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On the other hand it was also shown that
2019-04-20
On the other hand, it was also shown that multi-fraction long-course radiotherapy results in better re-calcification and fewer recurrences of spinal cord im 12 within the irradiated spinal region [24,25]. In case of recurrence, Nieder et al. [10] reviewed that re-irradiation of the spinal cord to a
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br Material and methods br Results
2019-04-20
Material and methods Results Thirty-one patients were enrolled consecutively, in this randomized study, between January 2010 and March 2012. The mean age was 65.5±13.7 years. The proportion of patients with primary prevention indication was 25.8% and ischemic cardiomyopathy was 29.0%. All repo
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