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          br In a detailed analysis using multiple2019-06-05  In a detailed analysis using multiple data sources in this issue of , Emily Keats and colleagues show that Kenya made some progress in reducing maternal and newborn mortality between 2003 and 2015, and made greater progress in reducing child mortality between 1998 and 2015, after earlier increases 
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          br Methods br Results br Discussion ICC2019-06-05  Methods Results Discussion ICC represents an aggressive malignancy arising from the intrahepatic biliary tree. Recent years have seen a dramatic increase in the incidence of ICC, making it the second most common primary liver cancer. Prognosis of ICC remains poor, with 5-year OS rates rangi 
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          br The L type calcium2019-06-05  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a geno 
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          br Case report A year old woman presented to our2019-06-05  Case report A 58-year-old woman presented to our hospital with a history of several weeks of chronic dry cough and intermittent shortness of breath. On physical examination, the patient\'s blood pressure was 135/85 mmHg, oral temperature was 37.4 °C, pulse rate was 112/min, and her respiratory ra 
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          It s finally a year by the end2019-06-01  It\'s finally 2015: a year by the end of which extreme poverty and hunger are to be eradicated, maternal and child mortality are to be drastically reduced, and the trajectory of the global incidence of HIV, tuberculosis, and malaria are to be reversed. Much has been written about where the Millenniu 
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          simvastin Additionally new resistance in a pathogenic bacter2019-06-01  Additionally, new resistance in a pathogenic bacterium with no treatment options should be notifiable under International Health Regulations to relevant authorities and control measures must be implemented without delay. This approach will work only if the new systems developing across the world, b 
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          Introduction Cancer therapy has evolved throughout the decad2019-06-01  Introduction Cancer therapy has evolved throughout the decades and is beginning to branch off into new and exciting fields including immunotherapy. The hope of this new field stems from the lack of success of chemotherapy in general. Chemotherapy\'s cytotoxic characteristics were regarded as one of 
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          Conversion of cholesterol to bile2019-06-01  Conversion of cholesterol to bile acids is the only significant catabolic pathway for elimination of excessive cholesterol in our body. Bile acids have long been recognized as important physiological agents that facilitate luteolin of dietary fats, steroids, drugs, and lipid soluble vitamins during 
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          Importa acentuar que la colonialidad no descansa sobre la2019-05-31  Importa acentuar que la colonialidad no descansa sobre la economía como tal, y menos sobre la literatura, sino sobre el devenir de la episteme racial gestada durante el legado colonial latinoamericano. Con ello busca no sólo, o no tanto, una relectura de la historia latinoamericana sino más bien una 
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          Se trata de concepciones diferentes2019-05-31  Se trata de concepciones diferentes de la democracia. Przeworski asume la democracia desde un concepto procesual centrado en las elecciones, y la define como “un régimen en el cual los cargos de gobierno se cubren como consecuencia de contiendas electorales. Un régimen sólo es democrático si se le p 
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          br Discussion To our knowledge we2019-05-31  Discussion To our knowledge, we report for the first time t(8;21) acute myeloid leukemia presenting as severe aplastic anemia. t(8;21)(q22;q22) is present in 5–10% of all AMLs, and includes variety of subtypes with varying pathology, and clinical presentations, ranging from circulating blast in p 
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          Missed cases have been reported who had2019-05-31  Missed cases have been reported who had an initially elevated C5DC concentration that normalized on a repeated sample. Such a result may be caused by secondary carnitine depletion. To avoid carnitine depletion, we propose that the carnitine loading test be used to assist diagnosis of GA-1. Although, 
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          Introduction Atrial fibrillation AF is2019-05-31  Introduction Atrial fibrillation (AF) is a common cardiac arrhythmia that becomes more prevalent with age [1] and is associated with an increased long-term risk of stroke, order JQ1 failure, and all-cause mortality [2]. Since Einthoven recorded the electrograms in 1906 [3], AF has widely been reco 
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          Although preoperative rehabilitation may have a strong impac2019-05-31  Although preoperative rehabilitation may have a strong impact on survival if additional patients are qualified for curative resection, yet strong evidence remains lacking to support the regimens for patients who have lung cancer. This may be due to, in part, the relatively brief meclofenamate of ti 
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          Two studies are ongoing that promise to be paramount in2019-05-31  Two studies are ongoing that promise to be paramount in the prescription of dexamethasone in the prophylaxis of pain flare. NCIC CTG is currently investigating the use of 8mg dexamethasone daily on the day of treatment and four days post-treatment versus placebo of the same duration (NCT01248585) [1 
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