• Bennet and colleagues also make an

  2019-05-06

  

  Bennet and colleagues also make an important addition to the literature on the Affordable Medicines Facility—malaria (AMFm) intervention, since a comparison of ACT treatment coverage for countries that had the AMFm intervention is made with those for countries that did not have the AMFm intervention

• Notwithstanding issues of equity improvement

  2019-05-06

  

  Notwithstanding issues of equity, improvement of research capacity in LMICs has practical benefits. People working and living in LMICs are better placed to define issues of importance to their populations than are people living thousands of miles away in HICs—who often fund research based on their o

• Since many decades bone tumours have stimulated imagination

  2019-05-06

  

  Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh

• br Materials and methods br Results

  2019-05-06

  

  Materials and methods Results Discussion Our results demonstrated that patients who underwent ICD implantation and received 15J-DT exhibited evidence of myocardial damage as indicated by increased serum c-TNT and H-FABP levels. On the other hand, ≤10J-DT (9J or 10J) was associated with an a

• Data on the costs of mental

  2019-05-06

  

  Data on the costs of mental disorders could motivate changes in mental health services. In the UK, economists and clinical researchers showed that increasing access to evidence-based psychological services (eg, cognitive behavioural therapy) would be nearly cost-neutral for the UK Government because

• Importa recordar que el intelectual acad mico siempre se ha

  2019-05-06

  

  Importa recordar que el intelectual académico siempre se ha sentido incómodo en su propia piel. Leer y escribir rigurosamente pueden ser actos radicales en sí, pero la relación del intelectual y la academia suele exigir sospecha, mucho más que la del artista y el mercado, o la del político y el part

• El estudio se realiza desde una perspectiva cualitativa a pa

  2019-05-05

  

  El estudio se realiza desde una perspectiva cualitativa, custom synthesis partir del análisis del discurso de entrevistas a miembros de los movimientos sociales, así como de declaraciones, discursos y otros textos vinculados tanto a gobiernos, como a los movimientos y sus respectivos proyectos y esp

• The patient refused either radiation therapy

  2019-05-05

  

  The patient refused either radiation therapy or systemic chemotherapy including rituximab and thus was initially treated with antibacterial therapy for HP infection. The first-line therapy consisted of lansoprazole 30mg, amoxicillin 750mg, and clarithromycin 200mg twice daily for 1 week. After 2 mon

• br Interaction between MSCs and immune cells MSCs have also

  2019-05-05

  

  Interaction between MSCs and immune cells MSCs have also been shown to possess broad immunoregulatory capabilities and are capable of influencing both adaptive and innate immune responses. MSCs inhibit immune silybin proliferation and maturation and suppress immune reactions both in vitro and in

• br Catheter ablation A reentry

  2019-05-05

  

  Catheter ablation A reentry circuit is supported by complex anatomy and a thick and/or damaged myocardium; thus, high-energy RF application is usually required to create the conduction block line through the critical isthmus of the reentry circuit in patients after ToF repair. A large-tip (8mm) a

• In this section we will try and address

  2019-05-05

  

  In this section we will try and address many of the frequently asked questions around preventive and prophylactic measures for patients either starting or already established on bone-targeted therapy (Figs. 2 and 3). In view of the difficulties in treating ONJ, preventive strategies would seem to ma

• butein br Future directions There is increasing

  2019-05-05

  

  Future directions There is increasing evidence that osteoblasts are important components of the bone metastatic niche, but their precise contribution in supporting tumour cell engraftment, dormancy and survival remains to be defined. Unlike osteoclasts, the role of osteoblasts in bone metastasis

• br Conclusions and future perspectives br Conflict of intere

  2019-05-05

  

  Conclusions and future perspectives Conflict of interest Author’s contributions Introduction Sulfotransferase (SULT)-mediated sulfation and steroid sulfatase (STS)-mediated desulfation represent two opposing mechanisms involved in regulating the chemical and functional homeostasis of end

• Although Afnan Holmes and colleagues

  2019-05-05

  

  Although Afnan-Holmes and colleagues\' report covers substantial ground, several issues remain unexamined. For example, why have facility delivery rates in the country stagnated at roughly 50% over the past decade? Although enhancement of women\'s agency in making health-care decisions is necessary,

• br Rheumatic heart disease RHD affects

  2019-05-05

  

  Rheumatic heart disease (RHD) affects over 32 million people worldwide; the vast majority of patients are in low-income and middle-income countries. It is a leading cause of premature mortality in children and young adults living in endemic regions. Patients with RHD often present in an advanced s

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